Observation on Human Allografts.

Histopathology of "fresh" human aortic valve allografts.

Gavin, J. B., Barratt-Boyes, B. G., Hitchcock, G. C., and Herdson, P. B. (1973). Thorax, 28, 482-487. Histopathology of 'fresh' human aortic valve allografts. Six aortic valve allografts were studied histologically after having functioned in patients as aortic valve replacements for 14 to 442 weeks. The grafts initially had been collected under sterile conditions from cadavers and stored in Han...

Early glomerular dysfunction in human renal allografts.

BACKGROUND The long-term outcome of renal allografts is characterized by a progressive deterioration of renal function and graft loss. Our aim was to determine early glomerular functional abnormalities, before they become clinically apparent. METHODS Glomerular hemodynamics and dextran sieving were characterized in 21 well-functioning cadaveric renal allograft recipients [normal glomerular fi...

Morphologic findings in human cardiac allografts.

Morphologic findings in human cardiac allografts from 13 patients are presented. In the acutely rejected cardiac allograft there was a cellular infiltrate consisting of large lymphocytes and varying numbers of polymorphonuclear leukocytes, eosinophils, and histiocytes in the myocardium and arterial intima. The coronary arteries frequently exhibited degeneration, acidophilia, and vacuolation of ...

Morphological monitoring of human small bowel allografts.

Histological Analysis of Human Meniscal Allografts

Background: Little is known about the biology of meniscal allograft transplantation in humans. In particular, little information is available about the phenotype of the cells that repopulate the allograft, whether an immune response is elicited against the graft, and whether the repopulating cells synthesize normal extracellular matrix components. Methods: A small biopsy specimen of the menisca...